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The role of nicotine in IBD: The severity of experimental colitis in mice is dependent on the presence of the α5 neuronal nicotinic acetylcholine receptor subunit (nAChR)

✍ Scribed by D. Rachmilewitz; F. Karmeli; M. Kedmi; A. Orr-Urtreger


Book ID
119629590
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
147 KB
Volume
32
Category
Article
ISSN
1590-8658

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Neuronal nicotinic acetylcholine recepto
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Neuronal nicotinic acetylcholine receptors (nAChRs) were expressed in J(enopus laevis oocytes after nuclear injection of complementary deoxyribonucleic acid (eDNA) expression vectors. The two receptor subtypes e4/nc~l and e3/nel were readily distinguishable from one another by ACh sensitivity and de