𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The role of NF1 in Schwann Cell development and tumor formation and the influence of steroid hormones and metabolites

✍ Scribed by Therese M. Roth; Poornapriya Ramamurthy; Fumi Ebisu; Kate F. Barald


Book ID
116976444
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
54 KB
Volume
306
Category
Article
ISSN
0012-1606

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


In vitro studies of steroid hormones in
✍ Lauren Fishbein; Xuelian Zhang; Lori B. Fisher; Hua Li; Martha Campbell-Thompson πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 209 KB

## Abstract The most common NF1 feature is the benign neurofibroma, which consists predominantly of Schwann cells. Dermal neurofibromas usually arise during puberty and increase in number throughout adulthood. Plexiform neurofibromas, associated with larger nerves, are often congenital and can be l

A mouse embryonic stem cell model of Sch
✍ Therese M. Roth; Poornapriya Ramamurthy; Fumi Ebisu; Robert P. Lisak; Beverly M. πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 741 KB

## Abstract The neurofibromatosis Type 1 (NF1) gene functions as a tumor suppressor gene. One known function of neurofibromin, the NF1 protein product, is to accelerate the slow intrinsic GTPase activity of Ras to increase the production of inactive rasGDP, with wide‐ranging effects on p21ras pathw

Plexiform-like neurofibromas develop in
✍ George Q. Perrin; Lauren Fishbein; Susanne A. Thomson; Stacey L. Thomas; Karen S πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 440 KB πŸ‘ 1 views

## Abstract Plexiform neurofibromas are peripheral nerve sheath tumors that arise frequently in neurofibromatosis type 1 (NF1) and have a risk of malignant progression. Past efforts to establish xenograft models for neurofibroma involved the implantation of tumor fragments or heterogeneous primary