✦ LIBER ✦

The role of NADPH in the regulation of glucose-6-phosphate and 6-phosphogluconate dehydrogenases in rat adipose tissue

✍ Scribed by Antonio Ayala; Isabel Fabregat; Alberto Machado

Publisher: Springer
Year: 1991
Tongue: English
Weight: 371 KB
Volume: 105
Category: Article
ISSN: 0300-8177
DOI: 10.1007/bf00230368

No coin nor oath required. For personal study only.

✦ Synopsis

Previous studies examining the regulation of the synthesis of G6PDH and 6PGDH in rat liver and adipose tissue have focused on the induction of these enzymes by different diets and some hormones. In rat liver these enzymatic activities seem to be regulated by a mechanism involving changes in the NADPH requirements. In this paper we have studied the effect of changes in the flux through different NADPH-consuming pathways on G6PDH and 6PGDH levels in adipose tissue and on the NADPH/NADP ratio. The results show that: I) an increase in the consumption of NADPH, caused by the activation of either fatty acid synthesis or detoxification systems which consume NADPH, is paralleled by an increase in the levels of these enzymes; II) when the increase in consumption of NADPH is prevented, the G6PDH and 6PGDH levels do not change.

📜 SIMILAR VOLUMES

Possible involvement of NADPH requiremen

Possible involvement of NADPH requirement in regulation of Glucose-6-Phosphate and 6-Phosphogluconate dehydrogenase levels in rat liver

✍ Antonio Ayala; Isabel Fabregat; Alberto Machado 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 683 KB

Glucose-6-phosphate dehydrogenase and NA

Glucose-6-phosphate dehydrogenase and NADPH-consuming enzymes in the rat olfactory bulb

✍ Enrica Biagiotti; Paola Ferri; Ralf Dringen; Paolo Del Grande; Paolino Ninfali 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 319 KB 👁 1 views

## Abstract The resistance to oxidative stress is a multifactorial reaction involving the clustering of transcriptionally regulated genes. Because glucose‐6‐phosphate dehydrogenase (G6PD), the principal enzyme responsible for reducing power, is highly expressed in the olfactory bulb (OB), it is of

Study of glucose 6-phosphate dehydrogena

Study of glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in the American Buffalo(Bison bison)

✍ S. N. Naik; D. E. Anderson 📂 Article 📅 1970 🏛 Springer 🌐 English ⚖ 186 KB

American buffalos have been studied for their hemoglobin and transferrin types, which show no detectable polymorphism (Braend and Stormont, 1963;Stormont, 1964). This report summarizes new data on erythrocytic glucose 6-phosphate dehydrogenase (G6PD) and 6-phosphogluconate dehydrogenase (6PGD) in th

The ontogeny of phosphogluconate dehydro

The ontogeny of phosphogluconate dehydrogenase and glucose 6-phosphate dehydrogenase in Japanese quails and chicken-quail hybrids

✍ E. S. Leung; L. E. Haley 📂 Article 📅 1974 🏛 Springer 🌐 English ⚖ 519 KB

The ontogeny of phosphoglueonate dehydrogenase in Japanese quails and chicken-quail hybrids was determined by vertical starch gel eleetrophoresis of pooled early embryos. The enzyme of maternal origin was found to be present at all stages of development. Paternal phosphogluconate dehydrogenase in pu

Effect of hydrocortisone on activity of

Effect of hydrocortisone on activity of hexokinase and glucose-6-phosphate and 6-phosphoglutonate dehydrogenases in the liver and adipose tissue of rabbits

✍ G. M. Daudova; I. B. Soliternova 📂 Article 📅 1974 🏛 Springer US 🌐 English ⚖ 132 KB

The influence of temperature on glucose-

The influence of temperature on glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase and the regulation of these enzymes in a mesophilic and a thermophilic cyanobacterium

✍ Henk J. Lubberding; Peter V. M. Bot 📂 Article 📅 1984 🏛 Springer 🌐 English ⚖ 645 KB

The activities and kinetics of the enzymes G6PDH (glucose-6-phosphate dehydrogenase) and 6PGDH (6-phosphogluconate dehydrogenase) from the mesophilic cyanobacterium Synechococcus 6307 and the thermophilic cyanobacterium Synechococeus 6716 are studied in relation to temperature. In Synechococcus 6307