The Role of N-nitrosamine in Carcinogenesis at the Ureterocolic Anastomosis
β Scribed by M. STEWART; M. J. HILL; R. C. B. PUGH; J. P. WILLIAMS
- Book ID
- 115192585
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 295 KB
- Volume
- 53
- Category
- Article
- ISSN
- 1464-4096
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Urinary diversion in both a rat model for ureterosigmoidostomy and in ureterosigmoidostomy patients result in an increased incidence of colon tumours. Bacterial and chemical investigations on feces-urine mixtures from both the rat model and ureterosigmoidostomy patients showed the presence of a comp
A number of important reactions involved in the formation and metabolism of N-nitrosamines have been studied using a modified reaction field method which treats the solute quantum mechanically and the solvent as a polarized dielectric.