Ca 2+, calmodulin-dependent myosin light chain phosphorylation is generally considered to be an important regulatory mechanism Of smooth muscle contraction. We investigated the length-dependence of myosin phosphorylation and active stress induced by K + depolarization in arterial smooth muscle by me
The role of myosin phosphorylation in the contraction-relaxation cycle of smooth muscle
β Scribed by M. Ikebe; D. J. Hartshorne
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 640 KB
- Volume
- 41
- Category
- Article
- ISSN
- 1420-682X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The temporal relationship between myosin phosphorylation, contractile force and ATPase activity was studied in skinned preparations from the guinea-pig Taenia coli. When free Calcium concentration [( Ca2+]) was increased from pCa (-log[Ca2+]) 9 to pCa 4.5 at low calmodulin concentration (0.05 microM
There is general agreement now that elevation of intracellular calcium ion concentration [( Ca2+]i) mediates the physiological actions of a number of hormones, neurotransmitters and other pharmacological agents. In smooth muscle one way by which these agents elevate [Ca2+]i and induce contraction in