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The role of multivalent cations in oligonucleotide cellular uptake

✍ Scribed by Susanna Wu-Pong

Book ID
111742122
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
483 KB
Volume
39
Category
Article
ISSN
1521-6543

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## Abstract Cationic 5,10,15,20‐tetrakis (1‐methyl‐4‐pyridyl) porphyrin was tested as a delivery agent for oligonucleotides. By using fluorescence microimaging, it has been shown that complexation of the porphyrin to the phosphorothioate analog of dT~15~ labeled by rhodamine enabled its nonendocyti