Expression of the multidrug resistance p
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Anne T. Nies; JΓΆrg KΓΆnig; Marion Pfannschmidt; Ernst Klar; Walter J. Hofmann; Di
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Article
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2001
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John Wiley and Sons
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French
β 1000 KB
Treatment of hepatocellular carcinoma (HCC) by chemotherapy is often impeded by the intrinsic multidrug resistance (MDR) of this frequent primary cancer of the liver. The MDR phenotype can be caused by ATP-dependent export of chemotherapeutic drugs across the plasma membrane being mediated by transp