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The role of modifications in oligonucleotides in sequence recognition by MvaI restriction endonuclease

✍ Scribed by Elena A. KUBAREVA; Claus-Dietmar PEIN; Elisaveta S. GROMOVA; Svetlana A. KUZNEZOVA; Vadim N. TASHLITZKI; Dieter CECH; Zoe A. SHABAROVA


Book ID
115125901
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
526 KB
Volume
175
Category
Article
ISSN
1432-1327

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## Abstract To elucidate the mechanism of action of restriction endonucleases __Mva__I and __Eco__RII a study was made of their interaction with a set of synthetic substrates in which the heterocyclic bases or the sugar–phosphate backbone had been modified; individual nucleotide residues had been r