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The role of MAPK in the biphasic dose-response phenomenon induced by cadmium and mercury in HEK293 cells

✍ Scribed by Changfu Hao; Weidong Hao; Xuetao Wei; Lina Xing; Jianjun Jiang; Lanqin Shang

Book ID
116920000
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
898 KB
Volume
23
Category
Article
ISSN
0887-2333

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## Abstract Previously, we have shown that the release of AIF from mitochondria is required for As~2~O~3~‐induced cell death in human cervical cancer cells, and that reactive oxygen species (ROS) is necessary for AIF release from mitochondria. In this study, we further investigated the role of MAPK