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The role of mammalian initiation factor eIF-4D and its hypusine modification in translation

โœ Scribed by John W.B. Hershey; Zeljka Smit-McBride; Joachim Schnier


Book ID
119119946
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
290 KB
Volume
1050
Category
Article
ISSN
0167-4781

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## Abstract Enterovirus (EV) infection has been shown to cause a marked shutoff of host protein synthesis, an event mainly achieved through the cleavages of eukaryotic translation initiation factors eIF4GI and eIF4GII that are mediated by viral 2A protease (2A^pro^). Using fluorescence resonance en