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The role of Lyt-2+ T cells in the regulation of autoimmunity in murine lupus

โœ Scribed by Wofsy, David


Book ID
123063960
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
755 KB
Volume
1
Category
Article
ISSN
0896-8411

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โœ Stanford L. Peng; Joe Craft ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer ๐ŸŒ English โš– 423 KB

MRL/Mp-lpr/lpr mice develop a spontaneous lupus syndrome, including hypergammaglobulinemia, autoantibodies, glomerulonephritis, and lymphadenopathy. To investigate the role of lymphocytes subsets in the pathogenesis of disease, lupus-prone MRL mice deficient in alpha beta T cells, gamma delta T cell