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The role of lysosomes in the hepatic accumulation and release of beryllium

✍ Scribed by David N. Skilleter; Roger J. Price


Book ID
115774661
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
638 KB
Volume
28
Category
Article
ISSN
0006-2952

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Role of lysosomes in hepatic accumulatio
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At therapeutic free concentrations (120-360 nM in rheumatoid arthritis), the accumulation ratio for chloroquine (7-chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]-quinoline; CQ) in viable isolated rat hepatocytes is 795 +/- 33, which is of the same order of magnitude as in vivo hepatic uptake in th