𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The role of LRP in mediating the synergistic pathological effects of apoE4 and amyloid-β in vivo

✍ Scribed by Frenkel, Moran; Zepa, Lia; Belinson, Haim; Herz, Joachim; Michaelson, Daniel M.


Book ID
122691978
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
45 KB
Volume
6
Category
Article
ISSN
1552-5260

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Astrocyte lipoproteins, effects of apoE
✍ Anne M. Fagan; David M. Holtzman 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 86 KB 👁 1 views

The genetic association between the E4 isoform of apolipoprotein E (apoE) and increased risk for Alzheimer's disease (AD) has prompted interest in the neurobiology of apoE and the possible relationship between lipoprotein metabolism in the brain and neurodegenerative disease. ApoE, a product of astr

Role of LRP in TGFβ2-mediated neuronal u
✍ Marni E. Harris-White; Zerlinde Balverde; Giselle P. Lim; Peter Kim; Sheryl A. M 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 467 KB

## Abstract There is increasing evidence that soluble amyloid‐β peptide (Aβ) uptake into neurons is an early event in the pathogenesis of Alzheimer's disease (AD). Identification of the early events leading to neuronal dysfunction is key to developing therapeutic strategies, but relative roles of r