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The role of kinesin, dynein and microtubules in pancreatic secretion

✍ Scribed by Jürgen Schnekenburger; Ina-Alexandra Weber; Daniela Hahn; Igor Buchwalow; Burkhard Krüger; Elke Albrecht; Wolfram Domschke; Markus M. Lerch

Publisher
Springer
Year
2009
Tongue
English
Weight
591 KB
Volume
66
Category
Article
ISSN
1420-682X

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✍ Konrad J Böhm; Stefan Russwurm; Nagib Ghaleb; Konrad Reinhart; Eberhard Unger 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 412 KB

Lipopolysaccharide (LPS) is a main trigger substance for the development of septic shock and multiple organ failure. We showed by turbidity measurements that LPS inhibits microtubule formation in a pH‐dependent manner. Inhibition was found to be not only due to sequestration of MAP2 by LPS, but also