The role of keratin filaments during nuclear envelope reassembly in Xenopus egg extracts
β Scribed by Bo Zhang; Ying Chen; Zhiyang Han; Hans Ris; Zhonghe Zhai
- Book ID
- 117109153
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 571 KB
- Volume
- 428
- Category
- Article
- ISSN
- 0014-5793
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## Abstract Eggs of __Xenopoecilus sarasinorum__ possess two distinct types of filaments on the surface of the egg envelope (chorion), long, attaching filaments restricted to the vegetal pole and weak, nonattaching filaments around the animal pole (micropyle). Both types are formed during oogenesis
We have used Xenopus egg extracts to investigate the effects of the antitumor drug daunomycin on DNA replication in vitro. Xenopus sperm nuclei replicated nearly synchronously in our egg extracts, thereby allowing us to determine the effects of the drug on both replication initiation and elongation.