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The role of iron regulatory proteins in mammalian iron homeostasis and disease

✍ Scribed by Rouault, Tracey A

Book ID: 109914098
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 908 KB
Volume: 2
Category: Article
ISSN: 1552-4450
DOI: 10.1038/nchembio807

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## Abstract Iron is essential for cell survival and function; yet excess iron is toxic to cells. Therefore, the cellular and whole‐body levels of iron are regulated exquisitely. At least a dozen proteins participate in the regulation of iron homeostasis. Hemochromatosis, a genetic disorder of iron