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The role of iron as a mediator of oxidative stress in Alzheimer disease

✍ Scribed by Rudy J. Castellani; Paula I. Moreira; George Perry; Xiongwei Zhu


Book ID
112009894
Publisher
IOS Press
Year
2012
Tongue
English
Weight
734 KB
Volume
38
Category
Article
ISSN
0951-6433

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Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mecha