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The role of interleukin-1 and the inflammasome in gout: Implications for therapy

✍ Scribed by Richard M. Pope; Jürg Tschopp


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
168 KB
Volume
56
Category
Article
ISSN
0004-3591

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Objective. To study the expression and production of interleukin-1␤-converting enzyme (ICE) in human normal and osteoarthritic (OA) cartilage and synovium, quantitate the level of ICE in OA chondrocytes, and examine the relationship between the topographic distribution of ICE, interleukin-1␤ (IL-1␤)