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The Role of Insulin-Like Growth Factor Binding Proteins

✍ Scribed by Holly, Jeff; Perks, Claire

Book ID: 121202222
Publisher: S. Karger AG
Year: 2006
Tongue: English
Weight: 228 KB
Volume: 83
Category: Article
ISSN: 0028-3835
DOI: 10.1159/000095523

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## Abstract The synthetic activity of chondrocytes in articular cartilage declines with age, possibly as a result of decreased sensitivity to anabolic growth factors such as insulin‐like growth factor‐I. The sensitivity of these cells to insulin‐like growth factor‐I is regulated, in pan, by the syn