Most attempts to engineer the properties of proteins have employed single or multiple substitution mutations, which typically produce minor changes in structure. Recent structural and stability studies of insertion and deletion mutants clearly indicate that relatively large structural perturbations
โฆ LIBER โฆ
The role of insertions/deletions in the evolution of the intergenic region betweenpsbA andtrnH in the chloroplast genome
โ Scribed by Jane Aldrich; Barry W. Cherney; Ellis Merlin
- Publisher
- Springer-Verlag
- Year
- 1988
- Tongue
- English
- Weight
- 886 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0172-8083
No coin nor oath required. For personal study only.
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## Abstract Patients with breast and/or ovarian cancer were screened for gross rearrangements in the __BRCA2__ gene by Southern hybridization, with exon 10 and a fragment of exon 11 used as probes. One breast cancer patient with a positive family history had a 6.2โkb deletion including exons 12 and
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