The role of immunostimulatory CpG-DNA in septic shock
✍ Scribed by Wagner, Hermann ;Lipford, Grayson B. ;Häcker, Hans
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 324 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0344-4325
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Immunostimulatory CpG DNA was self-assembled to form DNA hydrogels for use as a sustained delivery system for both intercalated doxorubicin (DXR) and immunostimulatory CpG motifs for cancer treatment. X-shaped DNA (X-DNA) was designed as a building unit, and underwent ligation to form DNA hydrogels.
## Abstract ## Background Immunotherapy using immunostimulatory CpG DNA could be a promising new therapeutic approach to combat refractory peritoneal dissemination. In the present study, we report the use of a mannosylated cationic liposomes/immunostimulatory CpG DNA complex (Man/CpG DNA lipoplex)