Natural killer (NK) cells have been at the forefront of immunology for two decades. During that time, a great amount of information about these cells has been obtained. They are important in antiinfectious and antitumoral defense and shape the adaptive immune response. In addition, they can act as i
The role of IL-18 in the modulation of matrix metalloproteinases and migration of human natural killer (NK) cells
β Scribed by Yukiko Ishida; Kiyoshi Migita; Yasumori Izumi; Kazuhiko Nakao; Hiroaki Ida; Atsushi Kawakami; Seigo Abiru; Hiromi Ishibashi; Katsumi Eguchi; Nobuko Ishii
- Book ID
- 116464547
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 212 KB
- Volume
- 569
- Category
- Article
- ISSN
- 0014-5793
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## Abstract The biological functions of matrix metalloproteinases (MMPs) extend beyond extracellular matrix degradation. Nonβproteolytic activities of MMPs are just beginning to be understood. Herein, we evaluated the role of proMMPs in cell migration. Employing a Transwell chamber migration assay,
## Abstract The human natural killer (NK) cell in peripheral blood is a nonβthymusβdependent, (Fc+ C3β), Igβbearing lymphocyte and is probably identical to the human K cell, although not requiring the Fc receptor, in contrast to the K cell, for the lytic process. The human NK cell in tonsil and lym