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The Role of Hypoxia in Stem Cell Differentiation and Therapeutics

✍ Scribed by Hamid Abdollahi; Lisa J. Harris; Ping Zhang; Stephen McIlhenny; Vikram Srinivas; Thomas Tulenko; Paul J. DiMuzio

Book ID
116705644
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
177 KB
Volume
165
Category
Article
ISSN
0022-4804

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## Abstract Noggin is a secreted protein that inhibits the binding of bone morphogenetic proteins (BMPs) to their cognate receptor. Its role in human mesenchymal stem cell differentiation has not been well studied. Here, we studied the effect of noggin on human mesenchymal stem cell differentiation