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The role of hypoxia-activated prodrugs in cancer therapy

โœ Scribed by William A Denny


Book ID
117782008
Publisher
The Lancet
Year
2000
Tongue
English
Weight
223 KB
Volume
1
Category
Article
ISSN
1470-2045

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Prodrug activation enzymes in cancer gen
โœ Manish Aghi; Fred Hochberg; Xandra O. Breakefield ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 202 KB ๐Ÿ‘ 2 views

Among the broad array of genes that have been evaluated for tumor therapy, those encoding prodrug activation enzymes are especially appealing as they directly complement ongoing clinical chemotherapeutic regimes. These enzymes can activate prodrugs that have low inherent toxicity using both bacteria