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The role of hydrophobic interations in the phospholipid dependent activation of protein kinase C

โœ Scribed by Snoek, G.T.; Feijen, A.; Hage, W.J.; van Rotterdam, W.; de Laat, S.W.

Book ID
123054500
Publisher
Elsevier Science
Year
1987
Weight
121 KB
Volume
23
Category
Article
ISSN
0277-5379

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Two polychlorinated hydrocarbons cause p
Two polychlorinated hydrocarbons cause phospholipid-dependent protein kinase C activation in vitro in the absence of calcium
โœ Susan A. Rotenberg; I. Bernard Weinstein ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 466 KB

Polychlorinated hydrocarbons known to be nongenotoxic carcinogens were screened as activators of protein kinase C (PKC)-beta 1 either at high concentrations of Ca2+ or in the absence of Ca2+ (i.e., with 1 mM ethylene glycol-bis(beta-aminoethyl ether) N,N,N',N',-tetraacetic acid). Of those compounds