## Abstract Head and neck cancer is the world's sixth most common cancer, but despite advances in treatment, there has been no significant decline in the mortality rate. In recent years, there has been mounting epidemiologic and experimental evidence of a role for human papillomavirus (HPV) as the
The role of human papillomavirus in head and neck cancer
β Scribed by CHRISTEL BRAEMER LAJER; CHRISTIAN VON BUCHWALD
- Book ID
- 109344061
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 95 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0365-5555
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Background. Human papillomaviruses (HPV) are known to cause cancers of the cervix and other anogenital tract sites. Molecular biology has provided some evidence as to the specific mechanisms involved in the HPV-related carcinogenesis. Epidemiologic and molecular biology studies have also suggested t
## Abstract ## Objectives/Hypothesis: Mortality for black males with head and neck squamous cell carcinoma (HNSCC) is twice that of white males or females. Human papillomavirus (HPV)βactive HNSCC, defined by the concurrent presence of highβrisk type HPV DNA and host cell p16^INK4a^ expression, is