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The role of human ADA2a in the regulation of p53 acetylation and stability

โœ Scribed by Jing Huang; Li Zhang; Lin Xiao; LanJun Xu; FanLei Hu; WenWei Shao; Wei Liu; XiaoNing Mo; TaiPing Shi; XiaoYan Qiu


Book ID
107372432
Publisher
Springer
Year
2011
Tongue
English
Weight
885 KB
Volume
56
Category
Article
ISSN
1001-6538

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## Abstract The tumor suppressor p53 is frequently mutated in cancer. We have investigated the regulation of P53 in p53 wild type mouse hepatoma cells (line 55.1c), in p53 heterozygeously mutated cells (56.1b) and in p53 defective cells (lines 56.1d, 70.4 and HUH7) under various experimental settin