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The role of HSP70 on ENPP1 expression and insulin-receptor activation

โœ Scribed by Antonella Marucci; Giuseppe Miscio; Libera Padovano; Watip Boonyasrisawat; Jose C. Florez; Alessandro Doria; Vincenzo Trischitta; Rosa Di Paola


Book ID
105796788
Publisher
Springer
Year
2008
Tongue
English
Weight
205 KB
Volume
87
Category
Article
ISSN
0946-2716

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Hsp110 and Grp170, members of the Hsp70
โœ Johnโ€„G. Facciponte; Xiang-Yang Wang; Johnโ€„R. Subjeck ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 357 KB

## Abstract Heat shock protein 110 (hsp110) and glucoseโ€regulated protein (grp170) act as antiโ€cancer vaccines when complexed to tumor antigens by heat shock. It has been proposed that receptors on antigenโ€presenting cells contribute to HSPโ€mediated immune responses. Here, we show that hsp110 binds