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The role of host PrP in Transmissible Spongiform Encephalopathies

✍ Scribed by Enrico Cancellotti; Rona M. Barron; Matthew T. Bishop; Patricia Hart; Frances Wiseman; Jean C. Manson

Book ID
116270537
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
701 KB
Volume
1772
Category
Article
ISSN
0925-4439

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πŸ“œ SIMILAR VOLUMES

Theoretical Analysis of the Implication
Theoretical Analysis of the Implication of PrP in Neuronal Death during Transmissible Subacute Spongiform Encephalopathies: Hypothesis of a PrP Oligomeric Channel
✍ YVES CHAPRON; JEAN-MICHEL PEYRIN; SERGE CROUZY; ALEXANDRE JAEGLY; DOMINIQUE DORM πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 English βš– 580 KB

Transmissible subacute spongiform encephalopathies (TSE) are animal and human neurodegenerative diseases. The nature of the transmissible agent remains unknown. The speci"c molecular marker of these diseases is the abnormal isoform of the prion protein (PrP). This protein is encoded by a cellular ge