The role of hepatitis E virus testing in drug-induced liver injury
β Scribed by H. R. DALTON; H. J. FELLOWS; W. STABLEFORTH; M. JOSEPH; P. H. THURAIRAJAH; U. WARSHOW; S. HAZELDINE; R. REMNARACE; S. IJAZ; S. H. HUSSAINI; R. P. BENDALL
- Book ID
- 108605133
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 105 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0269-2813
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Distinguishing drug-induced liver injury (DILI) from idiopathic autoimmune hepatitis (AIH) can be challenging. We performed a standardized histologic evaluation to explore potential hallmarks to differentiate AIH versus DILI. Biopsies from patients with clinically well-characterized DILI [n = 35, in
that infiltrating T cells are activated and produce inflamma-CD4 / T lymphocytes have been identified as being retory lymphokines. 3,4 In experimental autoimmune hepatitis, sponsible for organ damage in the murine model of ex-T-cell-mediated liver damage could be demonstrated. 5 Howperimental liver