The role of heparin self-association in the gelation of heparin-functionalized polymers
โ Scribed by Frances J. Spinelli; Kristi L. Kiick; Eric M. Furst
- Book ID
- 108069877
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 421 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0142-9612
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Heparin is a mixture of linear polysaccharides of undetermined sequence. Both biosynthetic data and computer simulation studies have established that each heparin polymer chain is comprised of oligosaccharides of defined sequence, representing ordered domains. One such ordered domain is
A number of inhibitors of intrinsic blood coagulation have been examined. Particular emphasis was placed on heparin, heparin analogues, and hirudin. These inhibitors interfere primarily with two clotting factors in the intrinsic clotting scheme. These include factor IX, and thrombin. Our data sugge