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The role of glutathione s-transferases, P-170 glycoprotein, multidrug resistance associated protein and iododeoxyuridine labelling index in chemotherapy resistance of stomach cancer

โœ Scribed by Schipper, DL; Wagenmans, MJM; Peters, WHM; Wils, JAJM; Wagener, DJT


Book ID
122513677
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
184 KB
Volume
114
Category
Article
ISSN
0016-5085

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While P-glycoprotein (Pgp) and multidrug resistance-associated protein 1 (MRP1) are known to be important in acquired doxorubicin resistance, the role of glutathione S-transferases (GST) remains unclear. Our study assessed roles of these 3 factors in a human drug-sensitive carcinoma cell line (HEp2)