The role of glucocorticoids in the induction of zinc-α2-glycoprotein expression in adipose tissue in cancer cachexia
✍ Scribed by Russell, S T; Tisdale, M J
- Book ID
- 109998411
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 161 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0007-0920
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## Abstract The paraneoplastic syndrome of cachexia is considered a degenerative chronic inflammatory disease, being deeply related to the increase of pro‐inflammatory factors, especially tumour necrosis factor alpha (TNF‐__α__). It is known that the adipose tissue is affected by cachexia and contr
A large number of observations point towards cytokines, polypeptides released mainly by immune cells, as the molecules responsible for the metabolic derangements associated with cancer-bearing states. Indeed, these alterations lead to a pathological state known as cancer cachexia which is, unfortuna