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The role of genetics and cigarette smoking in the development of pulmonary fibrosis

โœ Scribed by Mark P. STEELE; Marcy C. SPEER; Jim C. LOYD; Kevin K. BROWN; Aretha HERRON; Susan H. SLIFER; Lauranell H. BURCH; Momen WAHIDI; John A. PHILLIPS; Thomas A. SPORN; Holman P. MCADAMS; Marvin I. SCHWARZ; David A. SCHWARTZ

Book ID
108964410
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
31 KB
Volume
11
Category
Article
ISSN
1323-7799

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## Author's Reply: Clarification of Data on the Etiological Role of Cigarette Smoking in Pulmonary Fibrosis As predicted, Dr. Weiss has leaped to repeat and thus hopefully to defend his original illogical conclusions concerning an etiological role of cigarette smoking in pulmonary fibrosis [Weiss,

Presentation of data on pulmonary fibros
Presentation of data on pulmonary fibrosis and cigarette smoking
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In a recent commentary Kilburn [1981] concluded that "Critical analysis not only provides no support for this thesis (that cigarette smoke causes pulmonary fibrosis) but provides adequate reasons to bury the suggestion. " Kilburn's analysis was both erroneous and superficial. In 1963 Auerbach et al

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The effect of cigarette smoking on pulmonary function is highly variable. Some heavy smokers retain normal pulmonary function and others experience profound pulmonary function loss. The role of genotype in this process is unknown. We tested for gene by environment interaction (GxE) in smoking-associ