The role of gene conversion in preserving rearrangement hotspots in the human genome
β Scribed by Fawcett, Jeffrey A.; Innan, Hideki
- Book ID
- 122812067
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 554 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0168-9525
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Genome instability has been associated with progression of transformed cells to high tumorigenicity. Although genome instability may result from a variety of factors, some studies suggest that DNA in the region of a chromosome rearrangement can subsequently have much higher rates of DNA deletions or