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The role of GASP in the post-endocytic sorting and signaling of virally encoded chemokine receptor US28

โœ Scribed by Pia Tschische; Jennifer Whistler; Dawn Thompson; Lene Martini; Maria Waldhoer


Publisher
BioMed Central
Year
2008
Tongue
English
Weight
68 KB
Volume
8
Category
Article
ISSN
1471-2210

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US28 is a chemokine receptor encoded by the human cytomegalovirus (hCMV). It has been shown to be crucial for viral propagation. For instance, it is present on the viral envelope where it may serve as a cell-to-cell attachment factor through binding to the membrane-bound chemokine fractalkine. Most