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The role of focal adhesion complexes in fibroblast mechanotransduction during scar formation

โœ Scribed by Rustad, Kristine C.; Wong, Victor W.; Gurtner, Geoffrey C.


Book ID
120406884
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
832 KB
Volume
86
Category
Article
ISSN
0301-4681

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Hic-5 is a paxillin homologue with four LIM domains in its C-terminal region, localized mainly in focal adhesions in normal fibroblasts. Hic-5 is also known to associate with focal adhesion kinase (FAK) or the related CAKโค, and with vinculin. In the present study, we examined changes in Hic-5 and pa