𝔖 Bobbio Scriptorium
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The role of dynamic conformational ensembles in biomolecular recognition

✍ Scribed by Boehr, David D; Nussinov, Ruth; Wright, Peter E

Book ID
109913276
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
746 KB
Volume
5
Category
Article
ISSN
1552-4450

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✍ Melissa J. Bobeck; Gary D. Glick πŸ“‚ Article πŸ“… 2007 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 213 KB πŸ‘ 1 views

## Abstract 11F8 is a sequence‐specific monoclonal anti‐ssDNA autoantibody isolated from a lupus prone mouse that forms pathogenic complexes with ssDNA, resulting in kidney damage. Prior studies show that specificity is mediated by a somatic mutation from serine at ^31^V~H~ to arginine. Reversion b