Down-regulation of Bcl-2 enhances autoph
β
Xing-Ding Zhang; Ye Wang; Jun-Chao Wu; Fang Lin; Rong Han; Feng Han; Kohji Fukun
π
Article
π
2009
π
John Wiley and Sons
π
English
β 573 KB
## Abstract In vivo administration of the mitochondrial inhibitor 3βnitropropionic acid (3βNP) produces striatal pathology mimicking Huntington's disease (HD). However, the mechanisms of cell death induced by metabolic impairment are not fully understood. Previous studies showed that 3βNP triggered