The role of DNA methylation in mammalian development
β Scribed by Claire E. Senner
- Book ID
- 118498653
- Publisher
- Reproductive Healthcare Ltd
- Year
- 2011
- Tongue
- English
- Weight
- 253 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1472-6491
No coin nor oath required. For personal study only.
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## Abstract Epigenetic modification of the cytosine base of DNA by its methylation introduced the possibility that beyond the inherent information contained within the nucleotide sequence there was an additional layer of information added to the underlying genetic code. DNA methylation has been imp
## Abstract Despite thousands of articles about 5βmethylcytosine (m^5^C) residues in vertebrate DNA, there is still controversy concerning the role of genomic m^5^C in normal vertebrate development. Inverse correlations between expression and methylation are seen for many gene regulatory regions [H