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The role of desferrioxamine chelatable iron in rat liver mitochondrial dysfunction in chronic dietary iron overload

✍ Scribed by Daniela Ceccarelli; A.V. Kozlov; D. Gallesi; A. Tomasi; F. Giovannini; A. Masini

Book ID
108431199
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
538 KB
Volume
42
Category
Article
ISSN
1567-5394

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To clarify the pathogenesis of hepatic iron toxicity, we investigated the effect of chronic dietary iron overload on the expression of several genes in rat liver. After 10 wk of iron treatment, when only minor histological features of liver damage were appreciable, the level of pro-a.JI)-collagen mR