The Role of dead-end in Germ-cell Tumor Development
β Scribed by RUI ZHU; CHITRALEKHA BHATTACHARYA; ANGABIN MATIN
- Book ID
- 111483885
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 80 KB
- Volume
- 1120
- Category
- Article
- ISSN
- 0890-6564
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Cancer. Patients who present with widely metastatic germ cell tumors (GCTs) are characteristically treated with cisplatin-based chemotherapy. Depending on the patient population selected, approximately 70% of these patients will obtain a complete clinical response, with normalization of serum tumor
## Abstract Studies examining altered imprinted gene expression in cancer compare the observed expression pattern to the normal expression pattern for a given tissue of origin, usually the somatic expression pattern for the imprinted gene. Germ cell tumors (GCTs), however, require a developmental s