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The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia

โœ Scribed by Deepa B. Shankar; Jerry C. Cheng; Kentaro Kinjo; Noah Federman; Theodore B. Moore; Amandip Gill; Nagesh P. Rao; Elliot M. Landaw; Kathleen M. Sakamoto


Book ID
113523543
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
643 KB
Volume
7
Category
Article
ISSN
1535-6108

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## Abstract We have shown that the __CBL__ gene at 11q23.3, telomeric to __MLL__, was fused to __MLL__ in an adult patient with de novo acute myeloid leukemia (FABโ€M1). Southern blot analysis indicated that the __MLL__ rearrangement was involved in the chromosomal abnormality. cDNA panhandle polyme