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The Role Of Class Ii And Iii Viral Protein Transmembrane Domains (tmds) In Voltage-dependent Fusion

โœ Scribed by Markosyan, Ruben M.; Kielian, Margaret; Cohen, Fredric S.


Book ID
122165731
Publisher
Biophysical Society
Year
2009
Tongue
English
Weight
39 KB
Volume
96
Category
Article
ISSN
0006-3495

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Both the neuronal IIA as well as the cardiac SkM2 isoform of the pore forming alpha-subunit of voltage dependent sodium channels are modulated by Protein Kinase A. While alphaIIA becomes attenuated upon PKA stimulation, alphaSkM2 becomes upregulated. PKC dependent phosphorylation of a serine, locate