The role of calcium influx in cellular proliferation induced by interaction of endogenous ganglioside GM1 with the B subunit of cholera toxin
โ Scribed by Nancy E. Buckley; Yuan Su; Sheldon Milstien; Sarah Spiegel
- Book ID
- 115741489
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 867 KB
- Volume
- 1256
- Category
- Article
- ISSN
- 0005-2760
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๐ SIMILAR VOLUMES
The use of the B subunit of cholera toxin, a protein that binds specifically to ganglioside GM 1, has provided a new paradigm for studying physiological functions of ganglioside GMl . The B subunit inhibited the growth of rat glioma C6 cells that had been pretreated with ganglioside GM1. In some pre
The role of endogenous GM1 ganglioside in neurite outgrowth has been studied in N18 and NG108-15 neuroblastoma cells with the GM1-specific ligand cholera toxin B subunit (Ctx B), which stimulates Ca(2+) influx together with neuritogenesis. Our primary goal has been to identify the nature of the calc