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The role of calcium in cell injury

✍ Scribed by Benjamin F. Trump; Irene K. Berezesky; Wolfgang J. Mergner; Patricia C. Phelps

Publisher
Elsevier Science
Year
1978
Weight
130 KB
Volume
9
Category
Article
ISSN
0047-7206

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The mechanisms of hepatocyte injury caused by exogenous superoxide were investigated with the use of cultured rat hepatocytes. Cell viability, cytosolic free calcium concentration and cell surface structure were observed. Superoxide was produced by adding hypoxanthine and xanthine ozcidase to the bu