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The role of calcium and cyclic nucleotide signaling in cerebellar granule cell migration under normal and pathological conditions

✍ Scribed by Komuro, Yutaro; Galas, Ludovic; Lebon, Alexis; Raoult, Emilie; Fahrion, Jennifer K.; Tilot, Amanda; Kumada, Tasturo; Ohno, Nobuhiko; Vaudry, David; Komuro, Hitoshi

Book ID
126999785
Publisher
Wiley (John Wiley & Sons)
Year
2014
Tongue
English
Weight
812 KB
Volume
75
Category
Article
ISSN
1932-8451

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Ca2+ entry induced by N-methyl-D-aspartate (NMDA) in neurons and by noradrenaline (NA) in astrocytes is known to increase intracellular cyclic GMP (cGMP) levels through stimulation of the Ca2+-dependent nitric oxide synthase type I (NOS-I). The possibility that Ca2+ entry could also down-regulate in