Role of p53 family members in apoptosis
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M. Saeed Sheikh; Albert J. Fornace Jr.
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Article
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2000
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John Wiley and Sons
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English
โ 182 KB
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p53-mediated apoptosis involves multiple mechanisms. A number of p53-regulated apoptosis-related genes have been identified. Some of these genes encode proteins that are important in controlling the integrity of mitochondria while the others code for membrane death receptors. p53 may also induce apo