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The role of aromatase inactivators in the treatment of breast cancer

✍ Scribed by P. E. Lønning

Publisher
Springer
Year
2002
Tongue
English
Weight
89 KB
Volume
7
Category
Article
ISSN
1341-9625

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Estrogens are the major hormones supporting the growth of human breast cancer. Aromatization of androgen precursors in peripheral tissues, including the breast cancer itself, is the major source of estrogens in postmenopausal women. Therefore, inhibition of the aromatase enzyme offers an effective m