The role of aquaporin-4 in the blood–brain barrier development and integrity: Studies in animal and cell culture models
✍ Scribed by G.P. Nicchia; B. Nico; L.M.A. Camassa; M.G. Mola; N. Loh; R. Dermietzel; D.C. Spray; M. Svelto; A. Frigeri
- Book ID
- 116786629
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 604 KB
- Volume
- 129
- Category
- Article
- ISSN
- 0306-4522
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## Abstract Aquaporin‐4 (AQP4), a water channel protein, is abundantly expressed in astrocytes and plays a key role in the development of brain edema. However, it is not clear whether AQP4 contributes to astrocytic swelling in hypoxia–ischemia (HI). To investigate the roles of AQP4 in astrocytic sw